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Understanding how beta cells first form in the developing embryo is providing scientists with the know-how to make these cells in the lab. The hope is that lab-grown beta cells could, in the future, be used as a therapy for Diabetes. This animation creates a visual story of how we think the pancreas, which is the home of beta cells, forms. From small buds the pancreas develops into the intricate network of branches we see in an adult. Creative scientific experiments are, piece by piece, revealing the complex mechanisms that underpin this dynamic development.
Credits:
Animation: DEMCON Nymus3d http://www.nymus3d.nl/ / Scientific script and editor: Professor Anne Grapin-Botton http://danstem.ku.dk/research1/grapin... / Voice: Dr Robert Illingworth http://www.ed.ac.uk/mrc-human-genetic... / Voice edit and sound: Cameron Duguid http://www.cameronduguid.co.uk/ / Producer: Dr Cathy Southworth http://www.eurostemcell.org/biography...
With gratitude to our funders:
HumEn http://www.hum-en.eu/ This project, HumEn - Upscaling human insulin-producing beta cell production by efficient differentiation and expansion of endoderm progenitors - has received funding from the European Union’s Seventh Programme for research, technological development and demonstration under grant agreement No 602587
Revive http://www.revive.fr The consortium Revive is a selected project of the ANR "Laboratoire d'Excellence" programme (2011 - 2019) with research activity on stem cells in regenerative biology and medicine
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